Title of article :
Synthesis of silver nanoparticles using flavonoids: hesperidin, naringin and diosmin, and their antibacterial effects and cytotoxicity
Author/Authors :
Sahu, Nidhi National Environmental Engineering Research Institute (NEERI) - India , Soni, Deepika National Environmental Engineering Research Institute (NEERI) - India , Chandrashekhar, B National Environmental Engineering Research Institute (NEERI) - India , Satpute, D. B National Environmental Engineering Research Institute (NEERI) - India , Saravanadevi, Sivanesan National Environmental Engineering Research Institute (NEERI) - India , Sarangi, B. K National Environmental Engineering Research Institute (NEERI) - India , Pandey, R. A National Environmental Engineering Research Institute (NEERI) - India
Abstract :
Three different flavonoids -hesperidin, naringin
and diosmin (constituents of citrus plants) were used for
the synthesis of silver nanoparticles (AgNPs). Aqueous
solutions of pure flavonoids (0.2 mg mL-1
) mixed with
1 mM AgNO3 solution were exposed to bright sunlight to
prepare the nanoparticles. Characterization of the synthesized nanoparticles by UV–Visible spectrophotometer,
X-ray diffraction, Fourier transform infrared spectroscopy,
and transmission electron microscopy revealed that the
synthesized silver nanoparticles were 10–80 nm in size and
polydispersed in nature. Bactericidal effect against common pathogens and cytotoxicity of the synthesized silver
nanoparticles was investigated on human promyelocytic
leukemic (HL-60) cells. It is concluded that AgNPs synthesized using Naringin as reducing agent showed higher
stability and better antibacterial and cytotoxic activities.
Keywords :
Flavonoids , Nanoparticles , Bio-synthesis , Secondary metabolites , Reducing agents
Journal title :
Astroparticle Physics
