Author/Authors :
Manouchehri, Navid Isfahan Neuroscience Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Nehzat, Nasim Isfahan Neuroscience Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Mirmosayeb, Omid Isfahan Neuroscience Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Shaygannejad, Vahid Isfahan Neuroscience Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Barzegar, Mahdi Isfahan Neuroscience Research Center - Isfahan University of Medical Sciences, Isfahan, Iran
Abstract :
Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune neurological
disorder that is characterized by optic neuritis and longitudinally-extended transverse myelitis
lesions in spinal segments. Magnetic Resonance Imaging (MRI) findings are part of the diagnostic
process in NMOSD patients, and abnormal lesion patterns may cause deviation from a correct
diagnosis.
Clinical Presentation and Intervention: A 43-year-old female patient with abrupt cognitive loss,
motor dysfunction and tumefactive spread of the demyelinating lesions in her brain presented to the
Neurology Clinic of Kashani Hospital. Anti Aquaporine 4(AQP-4) antibody was observed, and the
patient responded well to the NMOSD treatment.
Conclusion: NMOSD can be considered a differential diagnosis during an episode of Fulminant
Demyelinating Disorder (FDD) with the tumefactive spread of the lesions.
