Cutaneous metastasis in a patient with adrenocortical carcinoma

Adrenocortical carcinoma is an uncommon and aggressive malignancy. Despite a high frequency of metastasis, cutaneous metastasis of adrenocortical carcinoma is rare with only isolated case reports. Its diagnosis can be challenging based solely on histopathological findings. Yet, the clinical history in combination with an immunohistochemical panel consisting of inhibin, vimentin, chromogranin, synaptophysin, melan- A, neuron specific enolase and calretinin, can be useful in differentiating it from other tumours with similar morphology. We report a case of a 52-year-old female who presented with subcutaneous nodules on her abdominal wall which, on histopathology, proved to be metastasis from adrenocortical carcinoma diagnosed one and a half years ago.