Author/Authors :
Saki, Nasrin Molecular Dermatology Research Center - Shiraz University of Medical Sciences, Shiraz - Dermatology Department - Shiraz University of Medical Sciences , Sari Aslani, Fatemeh Pathology Department - Shiraz University of Medical Sciences , Hajizadeh, Jalal Molecular Dermatology Research Center - Shiraz University of Medical Sciences, Shiraz - Dermatology Department - Shiraz University of Medical Sciences , Derayesh, Mohammad Molecular Dermatology Research Center - Shiraz University of Medical Sciences, Shiraz - Dermatology Department - Shiraz University of Medical Sciences , Kardeh, Bahareh Student Research Committee - Shiraz University of Medical Sciences
Abstract :
It is a challenging task to diagnose mycosis fungoides (MF), a
type of primary cutaneous lymphoma, in the early stages of its
development, due to the unspecific presentations associated
with the disease. Histopathology and immunohistochemistry
conduce to a more definite diagnosis. Presence of atypical T-cells
in epidermis and upper dermis is the most significant pathologic
finding. Herein, we present an 80-year-old lady with unusual
generalized lesions resembling prurigo nodularis for 3 years,
who was finally diagnosed as a case of MF with eosinophilic
infiltrations in her lesions and serum eosinophilia.