Title of article :
A review of three systemic retinoids in dermatology: acitretin, isotretinoin and bexarotene
Author/Authors :
Mortazavi, Hossein Department of Dermatology - Tehran University of Medical Sciences, Tehran , Aghazadeh, Nessa Department of Dermatology - Tehran University of Medical Sciences, Tehran , Ghiasi, Maryam Department of Dermatology - Tehran University of Medical Sciences, Tehran , Lajevardi, Vahideh Department of Dermatology - Tehran University of Medical Sciences, Tehran
Abstract :
Retinoids are synthetic and natural analogues of vitamin A that
have various effects on cellular differentiation, cellular proliferation,
immune system, and embryonic development. The present study
reviews the history of systemic retinoids in medicine, the structure
of synthetic retinoids and their mechanisms. The main focus is
on their biologic functions, clinical uses, and the adverse effects
of isotretinoin, acitretin, and bexarotene representing the most
commonly used first, second, and third generation systemic
retinoids, respectively.
Keywords :
acitretin , bexarotene , etretinate , isotretinoin , retinoids
Journal title :
Astroparticle Physics
