Author/Authors :
Abedi Elkhichi, Parisa Department of Microbiology- School of Medicine-Shahid Beheshti University of Medical Sciences,Tehran , dabiri, Hossein Department of Microbiology- School of Medicine-Shahid Beheshti University of Medical Sciences,Tehran , Nazemalhosseini Mojarad, Ehsan Gastroenterology and Liver Diseases Research Center- Research Institute for Gastroenterology and Liver Diseases- Shahid Beheshti University of Medical Sciences, Tehran , Rezasoltani, Sama Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center- Research Institute for Gastroenterology and Liver Diseases- Shahid Beheshti University of Medical Sciences, Tehran , Asadzadeh Aghdaei, Hamid Gastroenterology and Liver Diseases Research Center- Research Institute for Gastroenterology and Liver Diseases- Shahid Beheshti University of Medical Sciences, Tehran , Pouriran, Ramin School of Medicine- Shahid Beheshti University of Medical Sciences, Tehran , Nasiri, Mohammad Javad graguate
Abstract :
Colorectal cancer (CRC) has defined as the uncontrolled growth of cells in the
colon or rectum. The human colon contains the greatest number of microbes
Therefore; microbes may play an important role in the development of colorectal
cancer. Recent studies have shown an association between the microbial infection
and the risk of colorectal cancer. However, the results of these studies are
controversial. The nobility of the present study was to assess the prevalence of
Helicobacter pylori infection in the colorectal cancer in Iran. The biopsy were done
and the samples were obtained from patients suspected with colorectal cancer, from
2015 to 2017.Secondary, DNA of Helicobacter pylori was extracted by Commercial
kit. PCR was performed for Helicobacter pylori glmM gene eventually, the data was
analysed. A total of 86 patients in which 68 of them confirmed with CRC and 17
patients considered as controls. Of 68 biopsy specimens and control group, all of
them were negative for Helicobacter pylori. It was ultimately attained that in
colorectal cancer, there was no presence of Helicobacter pylori
