Author/Authors :
Nahidi, Yalda Cutaneous Leishmaniasis Research Center - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , Tayyebi Meibodi, Naser Cutaneous Leishmaniasis Research Center - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , Layegh, Pouran Cutaneous Leishmaniasis Research Center - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , Esmaeeli, Habiballah Faculty of Health - Mashhad University of Medical Sciences, Mashhad , Hosseini, Fatemeh Sadat Cutaneous Leishmaniasis Research Center - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad
Abstract :
Background: Melasma is a common acquired hyperpigmentation
disorder often appearing on the face of young women. Melasma
is classified into four groups based on Wood’s lamp examination:
epidermal, dermal, mixed, and indeterminate. The goal of this study
was to evaluate the relationship between clinicoepidemiological
characteristics of melasma and the level of involvement under
Wood’s lamp examination.
Method: In a cross sectional study, 50 melasma patients who
were visited at the dermatology clinic of Imam Reza Hospital
from March 2010 to September 2011 were studied. The level
of melasma involvement in all patients was determined using
a Wood’s lamp, and the patients’ information such as age,
occupation, location of melasma, marital status, pregnancy, oral
contraceptive pill consumption and Fitzpatrick skin type was
collected in a questionnaire.
Result: In single patients, dermal involvement and in married
patients, epidermal involvement was more common. Involvement
was more frequently dermal in jobs with exposure to sun and
more epidermal in indoor jobs. In the malar region, epidermal
involvement was more common. In patients with a history of
pregnancy, epidermal involvement was more prevalent as well,
while in the participants without a history of pregnancy, dermal
involvement was more frequent. In the pregnant patients with
melasma, epidermal involvement was more frequent. In patients
without a family history of melasma, epidermal involvement was
more frequently observed than the other two levels of involvement.
Conclusion: Based on the findings of this study, melasma in cases
with the involvement of the malar region, starting in pregnancy,
in patients without a family history of melasma, and in the
individuals who have indoor occupations is most likely to be
epidermal and may have a better response to treatment. On the
other hand, melasma in single persons and in those who have
outdoor occupations and are exposed to sun light is mostly dermal
with a worse response to treatment according to previous studies.
Keywords :
clinico-epidemiology , dermal involvement , epidermal involvement , melasma , wood’s lamp