Author/Authors :
Saki, Nasrin Department of Dermatology - Shiraz University of Medical Sciences, Shiraz , Sari Aslani, Fatemeh Molecular Dermatology Research Center - Shiraz University of Medical Sciences, Shiraz , Hemmatian Brojeni, Nahid Department of Dermatology - Shiraz University of Medical Sciences, Shiraz , Bahraminia, Sahar Student Research Committee - Shiraz University of Medical Sciences, Shiraz
Abstract :
A 52-year-old woman sought medical attention because of several
annular erythematous lesions with central clearing on her body since
seven months ago. No pruritus or burning sensations were noted.
Her medical and family history was unremarkable. Her Fitzpatrick
skin photo-type was II. On dermatological physical examination,
there were several annular erythematous plaques with raised borders
and central clearing on dorsal aspect of her hands, wrists, forearms,
and neck. (Figures 1 and 2) General physical examination was
unremarkable. An incisional skin biopsy was done from one of her
lesions including the normal skin, border, and center of the lesion.
Histological examination showed intact epidermis, and infiltration
of histiocytes and multinucleated giant cells centered in the mid
dermis. There were areas of almost complete loss of elastic fibers
surrounded by histiocyte aggregates. There was also mild to moderate
mainly lymphocytic infiltration around the vessels. Mucin deposition
was not seen (Figures 3 to 6).