Title of article
Relationship between lichen planus and dyslipidemia: A case-control study from Southwest Iran
Author/Authors
Yaghoobi, Reza Department of Dermatology - Ahvaz Jundishapur University of Medical Sciences, Ahvaz , Pazyar, Nader Department of Dermatology - Ahvaz Jundishapur University of Medical Sciences, Ahvaz , Kalantari, Hooman Department of Dermatology - Ahvaz Jundishapur University of Medical Sciences, Ahvaz
Pages
4
From page
11
To page
14
Abstract
Background: Lichen planus (LP) is a chronic inflammatory skin
condition which leads to changes in lipid metabolism. It may
cause chronic atherosclerosis and metabolic syndrome. The
objective of this study is to compare lipid levels of patients with
LP to healthy controls.
Methods: This case-control study recruited 100 total participants,
50 (25 male and 25 female) patients with LP and 50 healthy controls
admitted to the Dermatology Clinic of Imam Hospital, Ahvaz,
Iran. Serum triglyceride, total cholesterol, HDL cholesterol, and
LDL cholesterol levels were measured in samples drawn after a
12-hour fasting period.
Results: Patients with LP had significantly higher triglycerides
(147.7 vs. 118.4 mg/dl, P<0.05), total cholesterol (188 vs. 173 mg/
dl, P<0.05), LDL (122 vs. 106 mg/dl, P<0.05), and lower HDL (49
vs. 57 mg/dl, P<0.05) levels compared to controls.
Conclusion: This study showed an association between LP and
dyslipidemia. Screening of serum lipids in patients with LP might
be valuable to prevent cardiovascular diseases.
Keywords
cardiovascular , cholesterol , dyslipidemia , lichen planus , triglyceride
Journal title
Astroparticle Physics
Serial Year
2017
Record number
2480570
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