Author/Authors :
Bakhtiari, Sedigheh Oral Medicine Department - Dental School - Shahid Beheshti University of Medical Sciences, Tehran , Toossi, Parviz Dermatology Department - Medical School - Shahid Beheshti University of Medical Sciences, Tehran , Taheri, Jamileh Beigom Oral Medicine Department - Dental School - Shahid Beheshti University of Medical Sciences, Tehran , Azimi, Somayyeh International Research Collaborative Oral Health and Equity - Department of Anatomy - Physiology and Human Biology - School of Human Sciences - University of Western Australia, Australia , Kalantari Bengar, Mahnaz Dental School - Shahid Beheshti University of Medical Sciences, Tehran , Namazi, Zahra Tehran University of Medical Sciences, Tehran , Rafieian, Nasrin Dietary Supplements and Probiotic Research Center - Alborz University of Medical Sciences, Karaj
Abstract :
Background: ABO blood group antigens may play a role in
the pathophysiology of certain diseases. Several studies have
investigated the relation between blood group and autoimmune
disorders. In this research, we evaluated the associations between
ABO blood types and rhesus (Rh) factor in pemphigus patients.
Methods: In this case-control, hospital-based study, we evaluated
the prevalence of blood group on 110 pemphigus patients and
126 controls. The chi-square test was used to compare qualitative
variables and examine the relationship between blood groups
and Rh in pemphigus patients and a control group.
Results: Blood group (O) was found in 46.3% (O+ 38.2%) of
patients with pemphigus, followed by blood type A (30.0%; A+
27.3%), and blood groups B and AB. Compared to the control
group, we noted that the distribution of blood groups, with Rh
(P=0.73) or without Rh (P=0.52), did not significantly differ.
Conclusion: Although some associations between blood group
antigens and specific diseases have been reported in the literature,
this study did not find any statistically significant relationship
between blood groups and pemphigus disease.
