Title of article :
BK Nephropathy in Renal Transplant Patients with Epididymo-Orchitis
Author/Authors :
Moghtaderi, Mastaneh Pediatric Chronic Kidney Disease Research Center - Tehran University of Medical Sciences - Tehran, IR Iran , Abedzadeh, Aliasghar Tehran University of Medical Sciences - Tehran, IR Iran , Vasei, Mahmmad Pediatrics Centre of Excellence - Department of Pediatric Neurology - Children’s Medical Centre Hospital - Tehran University of Medical Sciences - Tehran, IR Iran
Abstract :
The patient was a 10-year-old male that was transplanted six months prior to this study. He was admitted because of epididymoorchitis,
pyuria, glucosuria, and rising blood urea nitrogen (BUN) and creatinine (Cr). BK viruria copy number was 50,000,000. In
renal biopsy examination, acute cellular rejection was reported. The diagnosis was BK virus epididymo orchitis with BK allograft
nephropathy. His treatment was started by discontinuation of tacrolimus and mycophenolate and starting of leflunomide and low
dose prednisolone. After improvement of renal dysfunction and BK load, the treatment regimen was changed to cyclosporine and
sirolimus. Renal function after the one-year follow up did not change and remained in a good condition
Keywords :
BK Virus , Renal Transplant , BK Nephropathy
Journal title :
Astroparticle Physics
