Author/Authors :
ansari - moghadam, alireza Health Promotion Research Center - Zahedan University of Medical Sciences, Zahedan, Iran , adineh, hossein Department of Epidemiology and Biostatistics - Iranshahr University of Medical Sciences, Iranshahr, Iran , zareban, iraj Health Education Department - Health Promotion Research Center - Zahedan University of Medical Sciences, Zahedan, Iran , almasy, zeinab Health Education Department - Health Promotion Research Center - Zahedan University of Medical Sciences, Zahedan, Iran , maghsudlu, mahtab Department of Thalassemia - Transfusion Research Center Tehran, Iran
Abstract :
Background: Thalassemia is acommongenetic disease in Iran and is most prevalent in northern and southern parts of the country.
Methods: Dueto vulnerable metabolic organs of thalassemia patients, the present studywasconducted to examine the relationship between Bone Mineral Density (BMD) and thyroid hormones along with some other variables.
Results: A total of 5491 (2647 males and 2634 females) cases were studied in Tehran (the capital of Iran), Sari (in northern Iran), Bandar Abbas, Iranshahr, and Zahedan (in southern Iran). The mean age ± standard deviation of the patients was 24.22 ± 12.7 years (24.4 ± 0.23 in both male and female patients).
Conclusions: Based on the results, 30.6% of the patients had lumbar osteoporosis, 39.0% had lumbar osteopenia, 8.6% had femoral neck osteoporosis, and40.4% hadfemoral neck osteopenia. Although thyroidhormonesdid not correlate withosteoporosis, greater changes were observed in these hormones in patients with thalassemia major than in other patients.
