Author/Authors :
Chetak, KB Department of Pediatrics - Jss Medical College - Jss Academy of Higher Education and Research - Mysore, India , Kumar, K Jagadish Department of Pediatrics - Jss Medical College - Jss Academy of Higher Education and Research - Mysore, India , Hiremath, Vilas Coagulation Specialist - Vijayashree Diagnostics - Cross - 3rd Block Koramangala Bangalore , Sujay, KR Jss Medical College - Jss Academy of Higher Education and Research - Mysore, India , Dinesh Kumar, US Jss Medical College - Jss Academy of Higher Education and Research - Mysore, India
Abstract :
Afibrinogenemia or hypofibrinogenemia is a quantitative defect in fibrinogen. It
is a rare disease with estimated frequency of 1 in 1,000,000 population. Routine
preoperative screening tests of coagulation disorders are insufficient to detect
subtle disorders of fibrinogen. Herein, we report a child who was supposed
to undergo open cardiac surgery for a large atrial septal defect. Preoperative
coagulation screening tests revealed minimal prolongation of prothrombin
time which made us do further work-up. Finally, she was diagnosed with
hypofibrinogenemia who was suggested to be congenital.
Keywords :
Thrombin time , Congenital hypofibrinogenemia , Afibrinogenemia Cardiac surgery , Coagulation screening tests , Prolonged prothrombin time
