Author/Authors :
Yazdanpanah, Hasan Pharmacology and Toxicology Department - School of Pharmacy - Shaheed Beheshti University of Medical Sciences and Health Services, Tehran , Eskandari Gheidari, Parvin Pharmacology and Toxicology Department - School of Pharmacy - Shaheed Beheshti University of Medical Sciences and Health Services, Tehran , Zarghi, Afshin Medicinal Chemistry Department - School of Pharmacy - Shaheed Beheshti University of Medical Sciences and Health Services, Tehran , Mirkarimi, Karim Food and Drug Control Labs - Ministry of Health and Medical Education, Tehran
Abstract :
Fumonisin B1 (FB1) is the most abundant of the fumonisin mycotoxins, mainly produced in corn by fungi of the genus Fusarium. FB1 has been shown to be hepatocarcinogenic and nephrocarcinogenic in animals. Contamination of corn with FB1 was assayed in samples collected from Mazandaran Province, situated on the Caspian littoral of Iran, in September 2000. In this survey, 38 corn samples were analyzed using HPLC, and all except one showed high levels of FB1 contamination ranged between 1.19 and 12.95 mg/kg. These results confirm the relatively high levels of FB1 contamination in corn of Mazandaran Province.
