Effects of Carbon Sources on Growth and Production of Antifungal Agents by Gymnopilus Spectabilis

Effects of different carbon sources on growth and production of antifungal agent(s) by Gymnopilus spectabilis were investigated. Different carbon sources including; Glucose, fructose, lactose, maltose, manitol and sucrose at the concentration of 10 g/l and slow releasing carbon sources including malt extract and soluble starch at the concentration of 2g/l were used. Inhibition of spore germination of Aspergillus niger was used to test antifungal activity. The results showed that the highest activity (90% inhibition of spore germination) and biomass concentration (2.4 g/l) were obtained when glucose was used as carbon source. Other media with different carbon sources showed antifungal activity ranging from 30% to 70% inhibition of spore germination. Combination of glucose with malt extract as a slow releasing carbon source was also increased activity to 100% inhibition.