The Effect of Fat Emulsion Intralipid 20% in Reproductive Outcome for Patients With Multiple Implantation Failure

Objectives: The aim of this study is to evaluate the effect of fat emulsion intralipid 20% on reproductive outcome of patients with multiple implantation failure (MIF). Materials and Methods: A retrospective study of 30 women with MIF who received intralipid 20% with in vitro fertilization, intracytoplasmic sperm injection (IVF-ICSI). The treatment cycle was conducted in reproductive endocrine and infertility medicine department (REIMD) at Women Specialized Hospital, King Fahad Medical City (KFMC), from January 2015 to December 2016. Results: Thirteen of 30 women (43.3%) had a positive pregnancy test and 17 (56.7%) did not. Pregnancy rate showed no statistically significant difference with the use of long protocol in comparison to short antagonist protocol. Use of intralipid 20% did not affect the embryo grading or yield the higher number of frozen embryos. Conclusions: MIF is a challenging situation in reproductive medicine. Intralipid 20% might be an effective treatment for patients with MIF.