Author/Authors :
Saffar, Hana APCP - Dept. of Anatomical and Surgical Pathology - Cancer Institute - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences - Tehran, Iran , Nili, Fatemeh APCP - Dept. of Anatomical and Surgical Pathology - Cancer Institute - Imam Khomeini Hoaspital Complex - Tehran University of Medical Sciences - Tehran, Iran , Sedighi Moghadam Pour, Azadeh APCP - Dept. of Anatomical and Surgical Pathology - Cancer Institute - Imam Khomeini Hoaspital Complex - Tehran University of Medical Sciences - Tehran, Iran , Moradi Tabriz, Hedieh APCP - Dept. of Anatomical and Surgical Pathology and Laboratory Medicine - Sina Hospital - Tehran University of Medical Sciences - Tehran, Iran , Sedighi Moghadam Pour, Parisa Radiologist - Guilan University of Medical Sciences - Guilan, Iran
Abstract :
Peripheral primitive neuroectodermal tumor (pPNET) is a highly aggressive small
round cell tumor belonging to PNET/Ewing sarcoma family. Ovarian tumors composed
of primitive neuroectodermal elements are extremely rare.
Herein we reported two cases of peripheral primitive neuroectodermal tumors
of ovary in two patients with different clinical presentations. Definite diagnoses
were made based on the histomorphology and immunohistochemistry
results.
With respect to different clinical behaviors, treatment modalities and prognosis
of peripheral primitive neuroectodermal tumors compared to other known ovarian
neoplasms, it is essential to consider this entity as a differential diagnosis in ovarian
tumors especially in young patients.
