Title of article
Combined Evaluation of AFP, CA15-3, CA125, CA19-9, and CEA Tumor Markers in Patients with Hepatitis B and C
Author/Authors
ASSMAR, Mehdi Dept. of Microbiology - Islamic Azad University, Lahijan , YEGANEH, Sara Dept. of Microbiology - Islamic Azad University, Lahijan , MANSOURGHANAEI, Fariborz Gastrointestinal and Liver Diseases Research Center - Guilan University of Medical Sciences, Rasht , MOZAFARI, Nour AMIR Dept. of Microbiology - School of Medicine - Iran University of Medical Sciences, Tehran
Pages
7
From page
1645
To page
1651
Abstract
Background: This study aimed to determine the role of tumor markers AFP, CA15-3, CA125, CA19-9 and CEA in patients with hepatitis B and C.
Methods: This descriptive cross-sectional study was performed from Oct 2012 to Oct 2014. Serum samples of 129 patients with hepatitis B and C referred to Guilan Liver and Digestive Disease Research Center in Rasht, Iran were collected and checked for the existence of the listed tumor markers by ELISA.
Results: No increase in serum levels of tumor marker CA19-9, CEA and CA15-3 were seen in patients with hepatitis (P>0.05). In patients with hepatitis B, increase in CA125 were observed (P=0.03). In hepatitis C patients, there was an increase in AFP levels (P=0.03).
Conclusion: The levels of AFP and CA125 markers were high in hepatitis C and hepatitis B, respectively. However, the increased levels were not seen is malignancy. Due to the small sample size, further study is necessary to find the reasons of the increase.
Keywords
Tumor markers , Hepatitis B , Hepatitis C , ELISA
Journal title
Astroparticle Physics
Serial Year
2016
Record number
2481726
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