Title of article :
Pharmaceutical Nanoemulsions and Their Potential Topical and Transdermal Applications
Author/Authors :
Abolmaali, Samira Sadat Department of Pharmaceutics - Faculty of Pharmacy - and Pharmaceutical Sciences Research Center - Shiraz University of Medical Sciences , Tamaddon, Ali Mohammad Department of Pharmaceutics - Faculty of Pharmacy - and Pharmaceutical Sciences Research Center - Shiraz University of Medical Sciences , Farvadi, Fakhr Sadat Department of Pharmaceutics - Faculty of Pharmacy - and Pharmaceutical Sciences Research Center - Shiraz University of Medical Sciences , Daneshamuz, Saeed Department of Pharmaceutics - Faculty of Pharmacy - and Pharmaceutical Sciences Research Center - Shiraz University of Medical Sciences , Moghimi, Hamidreza Department of Pharmaceutics - Faculty of Pharmacy - Shaheed Beheshti University of Medical Sciences, Tehran
Abstract :
Topical and transdermal drug delivery systems are noninvasive and can be selfadministered
with the minimization of side-effects, have received increased attention
during the past few years. Nanoemulsions, emulsions sized between 20-200 nm with
narrow distributions, offer several advantages for topical and transdermal delivery
of pharmaceutical agents including controlled droplet size, the ability to efficiently
dissolve lipophilic drugs, enhanced skin permeation and extended release of
lipophilic and hydrophilic drugs. Moreover, they exert good sensorial and physical
properties such as complete dispersion on skin and skin hydration in cosmetic
products. The review deals with nanoemulsion applications in topical and transdermal
drug and gene delivery.
Keywords :
Drug Delivery , Nanoemulsion , Nanotechnology , Skin , Topical , Transdermal
Journal title :
Astroparticle Physics
