Author/Authors :
Roozbayani, Mania Assistant Professor of Exercise Physiology - Department of Exercise Physiology - Borujerd Branch - Islamic Azad University, Borujerd
Abstract :
Recent research is about the role of miR-29 accompanied by various
conditions especially during the physical activity is a case of special
attention, such as high intensity interval training (HIIT) and
continuous aerobic training (CT) protective in heart, renal, lung, liver
and even immune system adaptation. Since recent studies indicated
the rolls of miR family on health and disease such as the effect of
miR on health parameters evaluation and cardiovascular-respiratory,
diabetic cardiomyopathy, diabetes, hypertension, myocardial
infarction, gastric and breast cancer. Blocking harmful genes such as
COL-1, CTGF, SMAD3, TGF-β, NFK-B and genes expression
related to health such as miR-29 is a primary approach in treatment
of some diseases. Meanwhile sports as HIIT and CT can be safe
approach for genes expression related health and blocking harmful
genes. This regulations applies by miRs especially miR-29 that is
one mystery regulator in variety of diseases. We will give a brief
account of relation between sports activities and miR-29 expression
in this review.
Keywords :
miR-29 , Sports medicine , Health , Disease , Gene regulation
