Title of article :
Evaluation of Antilipidperoxidation, Α-Amylase and Lipase Inhibitory Activity of Boswellia Ovalifoliolata Bal. Henry
Author/Authors :
Kumar, Dinakaran Sathis Aditya Institute of Pharmaceutical Sciences and Research, Surampalem, Andhra Pradesh, India , David, Banji Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh, India , Harani, Avasarala University College of Pharmacy - Andhra University, Visakhapatnam, Andhra Pradesh, India
Abstract :
The objective of the present study was to determine the antilipidperoxidation and in vitro α-amylase and lipase
inhibitory activity of the Boswellia ovalifoliolata Bal Henry (BOB) extract. The polyphenolic compounds,
flavonoids, and tannins content of the extracts were estimated by spectrophotometry. Antioxidant activity on goat
liver lipid peroxidation and linoleic acid was determined.Moreover, α-amylase and lipase inhibitory activities were
evaluated. All the extracts showed antioxidant, α-amylase, and lipase inhibitory properties. Among the other extracts
of BOB, macerated methanol extract could extract the highest concentration of polyphenols, flavonoids, and tannins.
Even macerated methanol extract showed antioxidant activity on goat liver lipid peroxidation and linoleic acid were
62.83±4.723 (p<0.01) and 56.67± 1.43 (p<0.01) respectively. Maximum α-amylase and lipase inhibitory activities
were expressed as 56.34±2.1 (p<0.01) and 79.36± 1.58% (p<0.01) respectively for macerated methanol and ethanol
extracts. The results indicated that all the extract exhibited low inhibition activity as compared to standard.
Keywords :
Boswellia ovalifoliolata Bal Henry , phenolic compounds , flavonoids , tannins , antioxidant , amylase , lipase
Journal title :
Astroparticle Physics