Title of article :
Allura Red, the Artificial Azo Dye, Inhibits Esterase Activity of Carbonic Anhydrase II: A Preliminary Study on the Food Safety in Term of Enzyme Inhibition
Author/Authors :
Khodarahmi, Reza Medical Biology Research Center - Kermanshah University of Medical Sciences , Ashrafi Kooshk, Mohammad Reza Medical Biology Research Center - Kermanshah University of Medical Sciences , Khaledian, Koestan Medical Biology Research Center - Kermanshah University of Medical Sciences
Abstract :
Allura red (AR) is a widely used colorant in food industry, but there is debate
on its potential security risk. In this study, in vitro inhibitory properties of the
dye against carbonic anhydrase (CA) were evaluated. The esterase activity of
purified CA decreased in the presence of AR, in a dose-dependent manner.
Regarding literature review and observed results, this preliminary study may
provide new horizons in safety of AR and the other dye additives.
Keywords :
Allura Red , Artificial Azo Dye , Carbonic Anhydrase II , Enzyme Inhibition
Journal title :
Astroparticle Physics
