Title of article :
Is IL1R1 required for celastrol s leptinsensitization and antiobesity effects?
Author/Authors :
Yao ، Yuan Tianjin University of Science Technology , Ma ، Long Tianjin University of Science Technology
Abstract :
The article by Xudong Feng et al. [1], published on 4 March 2019 in the journal of Nature Medicine, showed the relationship between natural product celastrol and obesity. The researchers demonstrated celastrol was able to sensitize leptin and displayed antiobesity effects through IL1R1 (Interleukin1 receptor 1). It was proved that IL1R1 was a gatekeeper for celastrol s metabolic actions.
Keywords :
IL1R1 , antiobesity
Journal title :
Traditional Medicine Research
Journal title :
Traditional Medicine Research
