Author/Authors :
Ranjbar, Reza Molecular Biology Research Center - Baqiyatallah University of Medical Sciences, Tehran , Rahbar, Mohammad Department of Microbiology - Iranian Reference Health Laboratories, Tehran , Naghoni, Ali Young Researchers Club - Karaj Branch, Islamic Azad University, Karaj , Farshad, Shohreh Professor Alborzi Clinical Microbiology Research Center - Shiraz University of Medical Sciences, Shiraz , Davari, Amin Molecular Biology Research Center - Baqiyatallah University of Medical Sciences, Tehran , Shahcheraghi, Fereshteh Department of Bacteriology - Pasteur Institute of Iran, Tehran
Abstract :
Background: Cholera has been a signicant public health challenge in many communities. An outbreak of acute diarrheal illness occurred
among participants in a wedding ceremony in a village in Qazvin, Iran, in 2008. We conducted an epidemiological, environmental and microbiological
investigation to determine the causative agent, source and extent of this outbreak.
Methods: Clinical and environmental samples were collected and analyzed for the presence of diarrhea-causing bacterial organisms, which
included Vibrio cholera. The relationship between the strains was determined using enterobacterial repetitive intergenic consensus polymerase
chain reaction (ERIC-PCR).
Results: The attack rate was 21.8%. Clinical and environmental samples were positive for V. cholerae serotype Inaba. All tested isolates had
a similar ERIC-PCR pattern, which indicated that a single clone of V. cholerae was responsible for this outbreak.
Conclusions: Our findings demonstrated that well water was the source of this outbreak.
