Response of Ischemia Modified Albumin (IMA) Plasma to the Time of Intensive Exercise (Morning and Evening) in Male Patients with Cardiovascular Disease

Introduction: Heart markers such as albumin are used for the fast and assured diagnosis of heart problems. However, the amount of this factor in response to exercise and in different times of the day is not determined. Therefore, the present study aimed to investigate the effect of training time (morning and evening) on ischemia-modified albumin (IMA) plasma levels in male patients with cardiovascular disease. Methods: 15 male patients with cardiovascular disease were chosen to participate in this quasi-experimental study. Before the outset of exercise protocol under specialist supervision, pre-test blood samples were taken from subjects at 7:00 in the morning. After taking blood samples, all participants took part in an exercise test until exhaustion. This test was designed based on Bruce protocol including 7 stages and each of these 3 minute stages followed predetermined speed and grade. One week later, subjects went through the same process at 7:00 in the evening. Paired sample t- test was used to analyze and compare pre-test and post-test means of each training period (morning and evening) and compare the mean of both times in the morning and in the evening. SPSS.20 was used to analyze study data. Results: there is no significant difference between pre-test means during morning and evening exercises (P=0.292). In addition to this, no significant relation was observed between post-test mean and three-hour-after test in the morning and evening, (P=0.185) and (P=0.250), respectively. Conclusion: Based on this study it could be said that circadian rhythm and circadian cycle have no severe effect on chemical responds and cardiac risk factors. Thus, cardiovascular patients can engage in their desired exercise during morning and evening.