Title of article :
Sonneratinone: A new antimicrobial benzofuranone derivative from the endophytic fungus Aspergillus niger isolated from the mangrove plant Sonneratia apetala Buch.- Ham
Author/Authors :
Nurunnabi ، Tauhidur Rahman Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences - Liverpool John Moores University , Al-Majmaie ، Shaymaa Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences - Liverpool John Moores University , Nahar ، Lutfun Laboratory of Growth Regulators - Institute of Experimental Botany ASCR - Palacký University , Nakouti ، Ismini Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences - Liverpool John Moores University , rahman ، S. M. Mahbubur Khulna University , Sohrab ، MD. Hossain Pharmaceutical Sciences Research Division - BCSIR Laboratories , Billah ، MD. Morsaline Khulna University , Ismail ، Fyaz MD. Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences - Liverpool John Moores University , Sharples ، George P. Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences - Liverpool John Moores University , Sarker ، Satyajit D. Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences - Liverpool John Moores University
Abstract :
A new antimicrobial benzofuranone derivative, named, sonneratinone (1), was isolated from the endophytic fungus Aspergillus niger, obtained from the leaves of Sonneratia apetala, a mangrove plant from the Sundarbans. Whilst the fungal strain was identified by macroscopic, microscopic and molecular techniques, the structure of the new compound was elucidated by spectroscopic means, e.g., 1D and 2D NMR, and HRESIMS. Sonneratinone (1) showed considerable antimicrobial activity against Micrococcus luteus, Staphylococcus aureus and Candida albicans in the resazurin 96-well microtitre plate antimicrobial assay.
Keywords :
Antimicrobial , Aspergillus niger , Benzofuranone , NMR , Resazurin assay , Sonneratia apetala , Sonneratinone
Journal title :
Trends in Phytochemical Research
Journal title :
Trends in Phytochemical Research
