Author/Authors :
HOJATI, H DEPARTMENT OF Surgery - Animal Lab - Pathology SHIRAZ UNIVERSITY OF MEDICAL SCIENCES, SHIRAZ , ANOUSH, F DEPARTMENT OF Surgery - Animal Lab - Pathology SHIRAZ UNIVERSITY OF MEDICAL SCIENCES, SHIRAZ , DEHGHAN, S DEPARTMENT OF Surgery - Animal Lab - Pathology SHIRAZ UNIVERSITY OF MEDICAL SCIENCES, SHIRAZ , TANIDEH, N DEPARTMENT OF Surgery - Animal Lab - Pathology SHIRAZ UNIVERSITY OF MEDICAL SCIENCES, SHIRAZ , KUMAR, P.V DEPARTMENT OF Surgery - Animal Lab - Pathology SHIRAZ UNIVERSITY OF MEDICAL SCIENCES, SHIRAZ
Abstract :
Tracheal defect repair is a challenging issue in surgery. A variety of prostheses have been used with little success.
Objective: To investigate the suitability of aorta for tracheal repair.
Methods: On the cervical trachea of 11 dogs we made a 5 cm long tracheal defect in the left posterior embranous portion. It was repaired by harvested infrarenal aorta and the aorta was replaced by Dacron graft. One dog died of heart failure, 8 were sacrificed 2 months and two 6 months after the procedure.
Results: Gross and microscopic study showed patent lumen with excellent re-vascularization of the aortic wall and ciliated columnar epithelial growth endoluminally.
Conclusion: Aortic graft is preferable to other substitutes because of its lower antigenicity, lower vascularities, as well as the absence of mucous secretions and peristalsis.
Keywords :
Aorta , Trachea , Repair , Graft