Author/Authors :
Yousofian, Saeed Children and Adolescent Health Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Miri-Aliabad, Ghasem Children and Adolescent Health Research Center - Zahedan University of Medical Sciences, Zahedan, Iran , Rostami, Tahere Tehran University of Medical Sciences and Health Services, Tehran, Iran , Mehrazma, Mitra Oncopathology Research Center - Tehran University of Medical Sciences, Tehran, Iran , Nematollahi, Pardis Cancer Prevention Research Center - Isfahan University of Medical Sciences, Isfahan, Iran
Abstract :
Acute lymphoblastic leukemia is the most common malignancy in children with a 5-year survival rate,
accounting for 80% of cases. Melanoma is rare in children and has been reported as a sporadically occurring
secondary malignant neoplasm in children with acute lymphoblastic leukemia. This study presented a 10-yearold
Iranian child with pre-B-cell acute lymphoblastic leukemia that was diagnosed at age 6. She was fully
recovered after 2 years of treatment. One year and six months after cessation of treatment, she was referred with
a 1×2 cm mass in her right parietal region of scalp. Biopsy of the lesion confirmed the diagnosis of malignant
melanoma. Computed tomography scan of the chest and abdomen also confirmed extensive liver metastasis
which was corroborated by liver biopsy. Bone scan also revealed bone metastases. Early diagnosis and treatment
of these tumors is extremely important and these patients should be closely monitored and undergo regular
physical examination.
