Author/Authors :
Goudarzipour, Kourosh Pediatric Congenital Hematologic Disorders Research Center - Shahid Beheshti University of Medical Science, Tehran, Iran , Mohammadi, Ahmad Pediatric Congenital Hematologic Disorders Research Center - Shahid Beheshti University of Medical Science, Tehran, Iran , Taherian, Reza Department of Radiology - Faculty of Medicine - Hamadan University of Medical Sciences, Hamadan, Iran , Arab Ahmadi, Mehran Department of Radiology - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences, Tehran, Iran , Behnam, Behdad Department of Internal Medicine - Firoozgar Hospital - Iran University of Medical Sciences, Tehran, Iran , Ayoobi Yazdi, Niloofar Department of Radiology - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences, Tehran, Iran
Abstract :
Acute lymphocytic leukemia (ALL) is one of the frequent malignancies in pediatrics and involves bone marrow
and extramedullary sites. Proptosis as extramedullary involvement of leukemia usually present in acute and
chronic myeloid leukemia. It is extremely rare for ALL to present initially as proptosis.Here, a-21-month-old
boy was presented with proptosis without any associated symptoms except lymphadenopathy. He was referred
with the impression of malignancy from an ophthalmologist. After bone marrow biopsy which showed 33%
blast cells, all positive for CD10, CD19, and CD79, the diagnosis of pre-B cell ALL was finally made. His
symptoms were improved completely 16 days after starting standard protocol for ALL.Afterone-year follow-up,
he was free of any symptoms.According to this initial presentation of ALL and no typical associated symptoms,
it is important to make rapid diagnosis and start the treatment in the childhood.
