Author/Authors :
FAKHRIEH KASHAN, Zohre Department of Medical Parasitology and Mycology - School of Public Health - Tehran University of Medical Sciences, Tehran , SHOJAEE, Saeede Department of Medical Parasitology and Mycology - School of Public Health - Tehran University of Medical Sciences, Tehran , KESHAVARZ, Hossein Department of Medical Parasitology and Mycology - School of Public Health - Tehran University of Medical Sciences, Tehran , ARBABI, Mohsen Department of Medical Parasitology - School of Medicine - Kashan University of Medical Sciences, Kashan , DELAVARI, Mahdi Department of Medical Parasitology - School of Medicine - Kashan University of Medical Sciences, Kashan , SALIMI, Mahbobeh Department of Medical Parasitology and Mycology - School of Public Health - Tehran University of Medical Sciences, Tehran
Abstract :
Toxoplasmosis the zoonotic disease with world-wide distribution is life-threatening in congenital from and in immunocompromised patients . According to seroepidemiological studies, 18%-85% of infection is reported from different parts of Iran . Both humoral and cellular immune systems are involved in T. gondii infection . In addition regulation role in calcium and phospho-rus metabolism, vitamin D is an immune-modulator . On the other hand 1, 25-(OH) 2 D can act as anti-proliferative agent in mononu-clear cells and reduce the production of IL2 and prevention of auto-immune diseases. Vita-min D deficiency is increasing in the world and it is estimated 70% in Iranian people .
