Author/Authors :
ZHANG, Zhiwei Department of Nursing - The Second Affiliated Hospital of Qiqihar Medical University - Qiqihar - Heilongjiang Province, China , LI, Bojun Nanchang University - Nanchang - Jiangxi Province, China , WANG, Zhichao Department of Academic Theory Research - Qiqihar Medical University, Qiqihar - Heilongjiang Province, China , WU, Lina School of Medical Technology - Qiqihar Medical University - Qiqihar - Heilongjiang Province, China , SONG, Lili Department of Anesthesiology - The Third Affiliated Hospital of Qiqihar Medical University - Qiqihar - Heilongjiang Province, China , YAO, Yexiang Department of Social Medicine and Health Management - School of Public Health - Qiqihar Medical University - Qiqihar - Hei-longjiang Province, China
Abstract :
Background: We aimed to systematically evaluate the efficacy of high-voltage pulsed current (HVPC) in the treatment of pressure ulcer.
Methods: We searched the databases of PubMed, Cochrane Library, Elsevier and EMBASE to identify ran-domized controlled studies on the application of HVPC in pressure ulcer treatment, up to January 2019. Two authors independently screened the literature according to the inclusion and exclusion criteria, extracted the data and evaluated the quality. RevMan 5.3 software was used for statistical analysis. Four randomized controlled trials involving a total of 176 patients were included in the study.
Results: Meta-analysis showed that the percentage of wound area reduction in the HVPC treatment group was higher than that in the control group (95%CI 24.59, 47.76, P<0.001). Descriptive analysis showed that there was no significant difference in wound healing between the HVPC treatment group and the control group. One study reported that there was contact dermatitis, and the rest of the studies reported no adverse events.
Conclusion: Compared with the conventional therapy, the combination with HVPC therapy can reduce the area of pressure ulcers more effectively. However, due to the small number of the studies included in this evalu-ation, the conclusions need to be verified by more high-quality studies.
