Author/Authors :
Ashrafi, Mahmoud Reza Department of Paediatrics, Division of Paediatric Neurology - Growth and Development Research Center, Children’s Medical Centre - Paediatrics Centre of Excellence - Tehran University of Medical Sciences, Tehran, Iran , Azizimalamiri, Reza Department of Paediatric Neurology - Golestan Medical, Educational, and Research Centre - Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran , Shervin Badv, Reza Department of Paediatrics, Division of Paediatric Neurology - Growth and Development Research Center, Children’s Medical Centre - Paediatrics Centre of Excellence - Tehran University of Medical Sciences, Tehran, Iran , Tavasoli, Ali Reza Department of Paediatrics, Division of Paediatric Neurology - Growth and Development Research Center, Children’s Medical Centre - Paediatrics Centre of Excellence - Tehran University of Medical Sciences, Tehran, Iran , Nikkhah, Ali Department of Paediatrics, Division of Paediatric Neurology - Growth and Development Research Center, Children’s Medical Centre - Paediatrics Centre of Excellence - Tehran University of Medical Sciences, Tehran, Iran , Montazerlotfelahi, Hadi Department of Paediatric Neurology - Imam Ali Hospital, Alborz University of Medical Sciences, Karaj, Iran , Vafaee-Shahi, Mohammad Paediatric Growth and Development Research Center - Institute of Endocrinology and Metabolism - Iran University of Medical Sciences, Tehran, Iran , Heidari, Morteza Department of Paediatrics, Division of Paediatric Neurology - Growth and Development Research Center, Children’s Medical Centre - Paediatrics Centre of Excellence - Tehran University of Medical Sciences, Tehran, Iran
Abstract :
Context: We are going to face an epidemic of severe acute respiratory syndrome coronavirus (SARS-CoV-2) virus in our country. The
main manifestation of this viral infection is respiratory and cardiovascular; however, up-to-date knowledge of its probable neurologic
complications is highly needed.
Evidence Acquisition: To provide up-to-date information on neurologic manifestation on coronaviruses, we concisely reviewed
the neurologic manifestations and their complications. Using the keywords, coronavirus, corona, human coronaviruses (HCoVs),
SARS, Middle East respiratory syndrome-related (MERS), coronavirus disease 2019 (COVID-19), manifestations, complications, and
neurologic, all the relevant articles were retrieved from PubMed, reviewed, and critically analyzed.
Results: Although the main clinical manifestation of human coronaviruses is respiratory involvement and the main cause of death
is acute respiratory failure, extra respiratory manifestations such as neurologic findings have been reported. Fortunately, the neurologic
manifestations in COVID-19 have not been reported yet.
Conclusions: We need well-designed studies to monitor neurologic manifestations of COVID-19 in adults and children.
Keywords :
Complications , Manifestations , Neurologic , Children , SARS-CoV-2 , COVID-19 , HCoVs
