Author/Authors :
Abedini, Atefeh Chronic Respiratory Diseases Research Center - National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Yassari, Fatemeh Chronic Respiratory Diseases Research Center - National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Taghavi, Kimia Chronic Respiratory Diseases Research Center - National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Abdi, Ebrahim Chronic Respiratory Diseases Research Center - National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Seifi, Sharareh Chronic Respiratory Diseases Research Center - National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Kiani, Arda Shahid Beheshti University of Medical Sciences - Tehran, Iran , Emami, Habib Shahid Beheshti University of Medical Sciences - Tehran, Iran
Abstract :
The frequency of kidney disorders varies in pulmonary
sarcoidosis patients. Since the prevalence of kidney disorders
among Iranian sarcoidosis patients is uncertain, this study aimed
to evaluate kidney disorders and associated manifestations in
Iranian pulmonary sarcoidosis patients.
Materials and Methods. One hundred patients with confirmed
granuloma as pulmonary sarcoidosis were studied for renal disorders.
Size of urinary tract and the presence of renal stones were checked
via clinical examination and urinary organ ultrasonography.
Patients’ 24-hour urine sample was examined for pH, calcium,
protein (over 250 mg) and creatinine (over 1.4 mg).
Results. Thirty-three percent of the patients expressed renal disorders
simultaneously.Uric acid in pulmonary sarcoidosis patients could
be correlated with the probability of developing renal stone. In
addition, 1,25-dihydroxyvitamin D levels above 30 ng/mL and
uric acid levels above 7 mg/dL in urine were directly correlated
with renal disorders in sarcoidosis patients.
Conclusions. Urinalysis is an easy and reliable method for assessing
renal disorders in sarcoidosis patients. The current study proposes
inclusion of urinalysis in routine checkups of sarcoidosis individuals.
Keywords :
nephritis sarcoidosis , Iran, granuloma , hypercalcemia , pulmonary sarcoidosis