Author/Authors :
MASHAYEKHI GOYONLO, Vahid Mashhad University of Medical Sciences, Mashhad , NOROUZY, Abdolreza Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , NEMATI, Mohsen Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , LAYEGH, Pouran Mashhad University of Medical Sciences, Mashhad , AKHLAGHI, Saeed Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , TAHERI, Ahmad Reza Mashhad University of Medical Sciences, Mashhad , KIAFAR, Bita Mashhad University of Medical Sciences, Mashhad
Abstract :
Background: Old world cutaneous leishmaniasis (CL) is known as a self-healing cutaneous parasitic infection. Host immunity has a fundamental role in the course of this infection. This study was designed to investigate the relationship between nutritional status and vitamin A intake with the clinical course of CL.
Methods: Overall, 250 patients with CL attending a dermatology clinic in Imam Reza Hospital Mashhad, Iran, were enrolled from Apr 2011 to Aug 2012. For data gathering, a semi-quantitative 302-item food frequency ques-tionnaire was utilized. They received routine treatment protocols for leishmaniasis and 1 year of follow-up
Results: As for the 149 patients who completed the study, a deficiency of macro and micronutrients, particularly vitamin A, was significantly related to a chronic clinical disease course.
Conclusion: Imbalanced or insufficient nutritional intake including vitamin A deficiency, may influence the clini-cal course of CL.
