Title of article
Evaluating the Frequency of Human T-Lymphotropic Virus Type 1 Infection in Iranian Population
Author/Authors
Ferdowsi, Shirin Blood Transfusion Research Center - High Institute for Research and Education in Transfusion Medicine, Tehran , Najafzadeh, Mahsa Student Research Committee - Birjand University of Medical Sciences, Birjand , Ameli, Mohammad Reza Blood Transfusion Research Center - South Khorasan Blood Transfusion Center, Birjand , Sajjadi, Mehdi Cellular and Molecular Research Center - Birjand University of Medical Sciences, Birjand
Pages
4
From page
47
To page
50
Abstract
Background: Human T-cell lymphotropic viruses 1 (HTLV1) is endemic in
specific regions. We aimed to determine the prevalence of HTLV I infection
among blood donors in southeast Iran.
Methods: This cross-sectional study was conducted between April 2005 and
March 2015. Sera were collected from blood donors and were tested for the
presence of HTLV1 specific antibody using ELISA. Reactive samples were then
tested by Western blot for confirmation.
Results: Of the 165,267 blood donors tested for HTLV 1 antibody, 45 (0.027%)
donors were positive. Out of 45 positive donors, 41 were first time blood donors,
3 were repeat blood donors and 1 as regular donor. Most HTLV-1-positive donors
were male and married. Co-infection with HBV was observed in one subject.
The percentage of positive samples had increasing patterns from 0.016% in 2009
to 0.084% in 2010 and decreased after that to 0.014% in 2015.
Conclusion: The results indicated a low level of infection of HTLV1 in this part
of our country.
Keywords
HTLV infection , Blood donors , Prevalence , Seropositivity
Journal title
Astroparticle Physics
Serial Year
2019
Record number
2487714
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