Title of article :
Analgesic, CNS Depressant and Anthelmintic Activity of Sarcostemma viminale
Author/Authors :
GIRME, ABOLI S Dept. of Pharmacognosy - Pravara Rural College of Pharmacy, Loni , NIRMAL, SUNIL A Dept. of Pharmacognosy - Pravara Rural College of Pharmacy, Loni , BHALKE, RASIKA D Dept. of Pharmacognosy - Pravara Rural College of Pharmacy, Loni , CHAVAN, MACHINDRA J Dept. of Pharmacognosy - Amrutvahini College of Pharmacy, Sangamner
Abstract :
Various extracts of Sarcostemma viminale were screened for central analgesic activity by hot plate test, peripheral analgesic activity by acetic acid-induced writhings, CNS depressant activity by pentobarbitone-induced sleep and locomotor activity testing methods and anthelmintic activity on the earthworms Pheretima posthuma . Results showed that petroleum ether and ethyl acetate extracts had good central analgesic activity; ethyl acetate and methanol extracts had good peripheral analgesic activity; chloroform and ethyl acetate extracts had good CNS depressant activity and methanol extract had good anthelmintic activity.
Keywords :
Sarcostemma viminale , Analgesic , CNS depressant , Anthelmintic , Photoactometer , Pheretima posthuma
Journal title :
Astroparticle Physics
