Author/Authors :
Taghavi, Sepideh Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, IR Iran , Alizadeh Sani, Zahra Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, IR Iran , Kasaii, Mohammad Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, IR Iran , Keshavarz, Mohammad Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, IR Iran , Naderi, Nasim Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, IR Iran , Amin, Ahmad Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, IR Iran , Chenaghlou, Maryam Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, IR Iran , Abshirini, Mahbobeh Medical Imaging Research Center - Department of Radiology - Shiraz University of Medical Sciences, Shiraz, IR Iran , Loghmani, Farane Rajaie Cardiovascular, Medical, and Research Center - Iran University of Medical Sciences, Tehran, IR Iran
Abstract :
Background: Chronic hypertension is one of the most important threats to public health in that it could
cause structural and functional myocardial dysfunction, leading to myocardial hypertrophy and
fibrosis. The early detection of cardiac remodeling due to hypertension has curative and
preventive advantages; in this regard, cardiac magnetic resonance imaging (CMR) is a helpful
modality.
Methods: In this cross-sectional descriptive study. 20 patients with heart failure and no other risk
factors, except hypertension, who were referred to the Heart Failure Clinic of Rajaie
Cardiovascular, Medical, and research Center between 2015 and 2017 were evaluated with
CMR. The left ventricular mass index (LVMI) was normal in 55% and increased in 45% of the
patients, and the left ventricular myocardial thickness (LVMT) was normal in 25% and
increased in 75%. Twenty-five percent of the patients had normal LVMI and LVMT.
Concentric remodeling was observed in 30% of the patients and 45% had concentric
hypertrophy. All the patients had an increased LV end-systolic volume index. LV
noncompaction without a specific fibrosis pattern was detected in 25% of the patients. Twentyfive
percent of the patients had a scattered pattern, possibly due to diffuse interstitial fibrosis.
Conclusions: In this study, most of the patients with hypertensive cardiomyopathy were in the normal
LVMI/LVMT or cardiac remodeling group and all of them had an increased LV end-systolic
volume index. Both of these findings are suggestive of increased wall stress, which could lead
to heart failure with a reduced ejection fraction and its progression.