Title of article
Effects of Turnera ulmifolia (Linn.) Leaves on Blood Glucose Level in Normal and Alloxan-Induced Diabetic Rats
Author/Authors
PRABU, D. Department of Pharmaceutics - C.L.Baid Metha College of Pharmacy, Thoraipakkam , NAPPINNAI, M. Department of Pharmaceutics - C.L.Baid Metha College of Pharmacy, Thoraipakkam , PONNUDURAI, K. Department of Pharmacology - Nandini Nagar Mahavidyalaya College of Pharmacy, India , THIRUGNANASAMBANTHAN, A. Department of Pharmaceutical Chemistry - K.L.E. Society’s College of Pharmacy, Rajajinagar , SRINIVASAN, S. Department of Statistics - Madras Christian College, Tamilnadu , RAMVIKAS, M. Department of Pharmaceutics - C.L.Baid Metha College of Pharmacy, Thoraipakkam
Pages
5
From page
77
To page
81
Abstract
The methanolic extract of leaves of Turnera ulmifolia L was evaluated for its effect on blood glucose in alloxan-induced diabetic and euglycemic rats. The extract were administered at three doses of 100, 200 and 400 mg/kg, p.o. Glibenclamide (10 mg/kg, p.o.) was used as standard for control group. In euglycemic rat, extract were administered at three doses of 100, 200 and 400 mg/kg, p.o. Extract at 400 mg/kg and glibenclamide significantly reduced blood glucose level in normal and alloxan-induced diabetic rats and raised the liver glycogen content significantly. This indicates that the leaves extract of Turnera ulmifolia L posses anti-hyperglycemic activity.
Keywords
Turnera ulmifolia , Euglycemic , Antihyperglycemic , Alloxan-induced diabetes , Rats
Journal title
Astroparticle Physics
Serial Year
2009
Record number
2488060
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