Author/Authors :
Shirvani, Ehsan Isfahan Cardiovascular Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, IR Iran , Sadeghi, Masoumeh Cardiac Rehabilitation Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, IR Iran , Hosseini, Mohsen Department of Biostatistics and Epidemiology - School of Public Health - Isfahan University of Medical Sciences, Isfahan, IR Iran , Khosravi, Alireza Hypertension Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, IR Iran , Rabiei, Katayoun Isfahan Cardiovascular Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, IR Iran , Rahimi, Mojtaba Department of Anesthesiology - School of Medicine - Isfahan University of Medical Sciences, Isfahan, IR Iran , Jafari-Koshki, Tohid Road Traffic Injury Research Center and Department of Statistics and Epidemiology - School of Health - Tabriz University of Medical Sciences, Tabriz, IR Iran , Shishehforoush, Mansour Isfahan Disaster Management Office - Isfahan Governer’s Office, Isfahan, IR Iran , Lahijanzadeh, Ahmadreza Khouzestan Department of Environment, Ahvaz, IR Iran , Moazam, Elham Cancer Prevention Research Center - Isfahan University of Medical Sciences, Isfahan, IR Iran , Mohebi, Mohammad Bagher Information Technology Offices - Isfahan University of Medical Sciences, Isfahan, IR Iran , Sarrafzadegan, Nizal Isfahan Cardiovascular Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, IR Iran
Abstract :
Background: This study aimed to evaluate the relationship between exposure to PM2.5 and the
number of hospital admissions due to cardiovascular diseases.
Methods: The present time-series, case-crossover study is a part of the CAPACITY study on
patients admitted to 15 hospitals in the Iranian city of Isfahan because of cardiovascular
diseases in 2012. PM2.5 concentrations were calculated in air pollution monitoring
stations and divided into 3 groups of good or moderate, unhealthy for sensitive people,
and unhealthy or hazardous. The relationship between the number of admissions and fine
particle concentrations was assessed.
Results: This study evaluated 15752 participants at a mean age of 59 ± 19.4 years. Men
accounted for 52.6% (n = 8282) of the study population. The mean concentration of fine
particles was 53.77 ± 29.65 micrometers. In most days of the year, the concentration of
PM2.5 was at an unhealthy level for sensitive people. Poisson regression analysis showed
a significant correlation between the number of hospital admissions due to cardiovascular
diseases and ischemic heart diseases and fine particle concentrations in the unhealthy
level for sensitive people (P = 0.001, P = 0.001, and P = 0.002). There was a significant
correlation between PM2.5 concentrations and the number of admissions due to
conductive heart diseases and heart blocks in unhealthy or hazardous levels (P = 0.02 and
P = 0.04).
Conclusions: The number of hospital admissions due to cardiovascular diseases can increase
during air pollution, especially when the concentrations of PM2.5 are elevated.
