Retinal Detachment in a Patient with Hydroxychloroquine Toxicity

A 67‑year‑old woman presented for a routine exam for glaucoma, initially diagnosed less than one year prior. Due to a history of lupus, she had taken hydroxychloroquine (Plaquenil®) 400 mg daily from 1995 to 2011. After losing a significant amount of weight without adjusting her dosage, she developed hydroxychloroquine toxicity, which produced a central scotoma in her right eye. She also underwent successful laser retinopexy for a retinal tear in 2011 in the right eye, followed by a vitrectomy for an idiopathic retinal hemorrhage in 2013. Cataract surgery with intraocular lens (IOL) placement was performed three months later.