Author/Authors :
Masiha, Hamid Private practis Metairie, USA , Nikpour, Heydar Ali Department of Plastic Surgery - Shiraz University of Medical Sciences, Shiraz, Iran , Hasani, Mohammad Esmaeil Department of Plastic Surgery - Tehran University of Medical Sciences, Tehran, Iran , Emami, Abolhasan Department of Plastic Surgery - Tehran University of Medical Sciences, Tehran, Iran , Jafari, Mehryar Tehran University of Medical Sciences, Tehran, Iran , Manafi, Ali Department of Plastic Surgery - Tehran University of Medical Sciences, Tehran, Iran
Abstract :
BACKGROUND Hemangioma is the most common tumor of neonatal period and it is almost always appeared by the end of the first week of life and can be found mostly in head and neck area. This study evaluated the synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma and arte-riovenous malformations. METHODS In this multicenter study, a combination of bleomycin, triamcinolone and epinephrine was injected intralesionaly for treatment of hemangiomas and arteriovenous malformations and their synergistic effect was evaluated in 32 patients. RESULTS Hemangiomas and low-flow arteriovenous malformations were treated well with their combination while port-wine spots and high-flow lesions response were relatively poor. CONCLUSION It seems that the combination of bleomycin, triamcinolone and epinephrine may be a good choice in treatment of hemangioma and arteriovenous malformations.
Keywords :
Bleomycin , Triamcinolone , Epinephrine , Hemangioma , Arteriovenous malformation
