Author/Authors :
Ghobadi, Farnaz Stem Cell and Transgenic Technology Research Center - Shiraz University of Medical Sciences, Shiraz, Iran , Mehrabani, Davood Stem Cell and Transgenic Technology Research Center - Shiraz University of Medical Sciences, Shiraz, Iran , Mehrabani, Golnoush Stem Cell and Transgenic Technology Research Center - Shiraz University of Medical Sciences, Shiraz, Iran
Abstract :
Recent findings in stem cell biology have opened a new window in regenerative medicine. The endometrium possesses mesenchymal stem cells (MSCs) called endometrial stem cells (EnSCs) having specific regenerative properties linked to adult stem cells. They contribute in tissue remodeling and engineering and were shown to have immuno-modulating effects. Many clinical trials were undertaken to ascertain the therapeutic potential of EnSCS. In this mini review, we showed that EnSCs are readily available sources of adult stem cells in the uterus that can be highlighted for their renewable multipotent and differentiation properties. This cell population may be a practical solution of choice in reproductive biology, regenerative medicine and autologous stem cell therapy.
