Author/Authors :
Aghamir, Mahmood Reza Department of Radiology and Radiotherapy - School of paramedical - Shahid Beheshti University of Medical Science, Tehran, Iran , Mehrabani, Davood Stem Cell and Transgenic Technology Research Center - Shiraz University of Medical Sciences, Shiraz, Iran , Amini, Masoud Department of Surgery - School of Medicine - Shiraz University of Medical Sciences, Shiraz, Iran , Mosleh-Shirazi, Mohammad Amin Department of Radiotherapy - Nemazee Hospital - Shiraz University of Medical Sciences, Shiraz, Iran , Nematolahi, Samaneh Department of Biostatistics - School of Medicine - Shiraz University of Medical Sciences, Shiraz, Iran , Shekoohi-Shooli, Fatemeh Department of Radiology and Radiotherapy - School of paramedical - Shahid Beheshti University of Medical Science, Tehran, Iran , Mortazavi, Mohammad Javad Ionizing and Non-Ionizing Radiation Protection Research Center - Shiraz University of Medical Sciences, Shiraz, Iran , Razeghian Jahromi, Iman Stem Cell and Transgenic Technology Research Center - Shiraz University of Medical Sciences, Shiraz, Iran
Abstract :
Acute radiation syndrome (ARS) is called as radiation sickness or radiation toxicity caused by abnormally high exposure to ionizing radiation in a very short period of time.1 High doses of ionizing radiation are able to contribute to detrimental systemic effects in different organs.2 In treatment of patients with ARS, physicians have used growth factors, cytokines and bone marrow transplantation.3 Mesenchymal stem cells (MSCs) have the potential for multilineage differentiation.4,5 Bone marrowderived stem cells (BMSCs) are the most well- known type of the mesenchymal stem cells used with safety and efficacy in several diseases such as ARS.1 The present study assessed the regenerative effect of bone marrow-derived stem cells on cell count and survival in Acute Radiation Syndrome.
Keywords :
Acute radiation syndrome , Mesenchymal stem cells , Bone marrow , Survival , Cell count
