• Title of article

    Application of Green Chemistry in the Synthesis of Thiopyran Derivatives

  • Author/Authors

    Sheikholeslami-Farahani, Fatemeh Department of Chemistry - Firoozkooh Branch, Islamic Azad University, Firoozkooh

  • Pages
    5
  • From page
    47
  • To page
    51
  • Abstract
    An efficient synthesis of 2H-thiopyran derivatives via three-component reaction of alkyl propiolate, benzoyl isothiocyanate or its derivatives and alkyl bromides in the presence of triphenylphosphine in water at 80o C without using any catalyst in water is described. The method offers several advantages including high yields of products and an easy work-up procedure.
  • Keywords
    Triphenyl Phosphite , Dialkyl Acetylenedicarboxilates , Multicomponent reactions , Triethyl phosphite
  • Serial Year
    2014
  • Record number

    2494298