Title of article :
Sodium Bismuthate: An Efficient Catalyst for the One-pot Synthesis of Biologically Active Spiro[4H-pyran] Derivativesunder Solvent-free Conditions
Author/Authors :
Mohamadpour, Farzaneh Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan , Maghsoodlou, Malek Taher Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan , Heydari, Reza Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan , Lashkari, Mojtaba Faculty of Science - Velayat University, Iranshahr
Abstract :
An efficient sodium bismuthate (NaBiO3) synthesis of biologically active spiro[4H-pyran] derivatives has been accomplished via one-pot three-condensation of isatin/acenaphthequinone, malononitrile and different reagents including 1,3-dicrbonyl compounds, α-naphthol and 4-hydroxycumarin under solvent-free conditions. The notable advantages of the present procedure are: eco-friendly, environmentally benign nature,low-cost and non-toxic catalyst, simplicity of operation with no necessity of chromatographic purification steps, short reaction times, good to high yields and solvent-free conditions.
Keywords :
Sodium bismuthate (NaBiO3) , Spiro[4H-pyran]derivatives , Biologically active compounds , Solvent-free conditions , One-pot operation
