Author/Authors :
Mohamadpour, Farzaneh Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan , Maghsoodlou, Malek Taher Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan , Heydari, Reza Department of Chemistry - Faculty of Science - University of Sistan and Baluchestan, Zahedan , Lashkari, Mojtaba Faculty of Science - Velayat University, Iranshahr
Abstract :
A mild and efficient synthesis of polysubstituted dihydro-2-oxypyrroles has been developed for the one-pot, four-component domino condensation of dialkyl acetylenedicarboxylate, formaldehyde and aromatic amines using Vanadium (V) oxide as the catalyst at ambient temperature. The use of Vanadium (V) oxide makes this process simple, more convenient, and environmentally friendly.
Keywords :
Vanadium (V) oxide , Dihydro-2-oxypyrrole derivatives , Multi-component reactions , Eco-Friendly