Title of article :
Application of Water for Synthesis of Cyclopentadienes via Multi-component Reactions of N-methyl imidazole
Author/Authors :
Ahmadi Agh Mashhadi, Alireza Department of Chemistry - Qaemshahr Branch, Islamic Azad University, Qaemshahr , Hossaini, Zinatossadat Department of Chemistry - Qaemshahr Branch, Islamic Azad University, Qaemshahr
Abstract :
A water-accelerated multi-component synthesis of organic target molecules was used as a key method for the preparation of cyclopentadiene derivatives. The three-component condensation reactions of primary amines with alkyl propiolates in the presence of N-methylimidazole in water at room temperature were developed as efficient and clean green synthetic procedures for the high-yielding preparation of 4-oxo-2,5-cyclopentadiene-1,2-dicarboxylate derivatives.
Keywords :
Primary amines , N-methylimidazole , Alkyl propiolates , Multi-component reaction , Water
