Author/Authors :
Pahlavan, Rokhsar Department of Chemistry - Qaemshahr Branch, Islamic Azad University, Qaemshahr , Najafi, Maedeh Department of Chemistry - Qaemshahr Branch, Islamic Azad University, Qaemshahr , Hossaini, Zinatossadat Department of Chemistry - Qaemshahr Branch, Islamic Azad University, Qaemshahr
Abstract :
An efficient synthesis of isoquinoline-2,3-dicarboxylates is described via one-pot reactions of isoquinoline and alkyl bromids with dialkyl acetylenedicarboxylates in water at 70oC. The mild reaction conditions and high yields of the products exhibit the good synthetic advantage of these methods.
Keywords :
Water , One-pot reactions , Isoquinoline , phenacyl bromids
