Title of article :
Green Synthesis of N-pyrroles in Water via Using ZrOCl2.8H2O as an Efficient and Eco-Friendly Catalyst
Author/Authors :
Ghafuri, Hossein Department of Chemistry - Iran University of Science and Technology, Tehran , Emami, Atefeh Department of Chemistry - Iran University of Science and Technology, Tehran
Abstract :
A simple and efficient protocol for the synthesis of N-substituted pyrroles from one-pot condensation reaction of 2, 5-dimethoxytetrahydrofuran with aryl/alkyl, sulfonyl and acyl amines in the presence of ZrOCl2•8H2O in water has been developed. This new method has the advantages of simple experimental and work-up procedure, high to excellent yields, easy availability, economical, eco-friendly of the catalyst and high catalytic activity.
Keywords :
Dimethoxytetrahydrofuran , Amines , N-substituted pyrrole , Zirconiumoxychloride , Green synthesis , Water as solvent
