Title of article :
Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria
Author/Authors :
Barati, Mitra Research Center of Pediatric Infectious Diseases - Institute of Immunology and Infectious Diseases - Iran University of Medical Sciences , MIRKALANTARI, SHIVA Department of Microbiology - Faculty of Medicine, Iran University of Medical Sciences , Ansari, Saham Department of Parasitology and Mycology - School of Medicine - Shahid Beheshti University of Medical Scienses , SALARI, SAMIRA Student Research Committee - Kerman University of Medical Sciences , Fattahi, Azam Center for Research and Training in Skin Disease and Leprosy - Tehran University of Medical Sciences
Abstract :
Background: The present study was conducted to determine antimicotic susceptibility of Candida species (sp.) from patients with
symptomatic candiduria. Materials and Methods: Identification of Candida sp. and determination of efficacy of most routine
antifungals were done using polymerase chain reaction‑restriction fragment length polymorphism method and E‑test, respectively.
Results: The results from susceptibility test reveal that caspofungin and amphotericin B have high antifungal activity against both
albicans (100% and 96%, respectively) and nonalbicans (95.11% and 72.72%, respectively) isolates. Conclusion: The present study
suggests that caspofungin and amphotericin B have the excellent ability to eradicate both Candida groups that showed decreased
susceptibility to other compounds.
Keywords :
Antifungal drugs , Candida species , polymerase chain reaction‑restriction fragment length polymorphism , symptomatic candiduria
Journal title :
Journal of Research in Medical Sciences
